Surgical Neurology
Volume 65, Issue 1 , Pages 42-47 , January 2006

Comparative dural closure techniques: a safety study in rats

  • Pinar Akdemir Ozisik, MD

      Affiliations

    • Department of Neurosurgery, Hacettepe University Faculty of Medicine, 06100 Ankara, Turkey
    • Corresponding Author InformationCorresponding author. Tel.: +90 312 3051715; fax: +90 312 3111131. 311 West Franklin St., Apt 902, Richmond, VA 23220, USA. Tel.: +1 804 8284337; fax: +1 804 8271536.
    • ,
  • Servet Inci, MD, PhD

      Affiliations

    • Department of Neurosurgery, Hacettepe University Faculty of Medicine, 06100 Ankara, Turkey
    • ,
  • Figen Soylemezoglu, MD

      Affiliations

    • Department of Pathology, Hacettepe University Faculty of Medicine, 06100 Ankara, Turkey
    • ,
  • Hilmi Orhan, MD

      Affiliations

    • Department of Toxicology, Hacettepe University Faculty of Pharmacy, 06100 Ankara, Turkey
    • ,
  • Tuncalp Ozgen, MD, PhD

      Affiliations

    • Department of Neurosurgery, Hacettepe University Faculty of Medicine, 06100 Ankara, Turkey

Received 11 March 2005 ,Accepted 25 April 2005.

  • Image Result

    A: Photomicrograph showing mixed inflammatory cell infiltration (arrowhead) in the leptomeninges in the control subgroup signifying cell type +2 (hematoxylin and eosin staining, ×200). B: Spindle-shap

    A: Photomicrograph showing mixed inflammatory cell infiltration (arrowhead) in the leptomeninges in the control subgroup signifying cell type +2 (hematoxylin and eosin staining, ×200). B: Spindle-shaped cells forming fascicles (arrowhead) 14 days after application of tissue adhesive (methyl-metacrylate) signifying cell type +4 (hematoxylin and eosin staining, ×200). C: Well-formed capillaries (arrowhead) and surrounding fibroblastic activity (arrows) 14 days after application of tissue adhesive (fibrin glue) signifying +4 vascularization (hematoxylin and eosin staining, ×200). D: Extracellular matrix deposition (arrows) with decreased cellularity 14 days after application of tissue adhesive (CO2 laser) signifying +5 collagen deposit (hematoxylin and eosin staining, ×200).

  • Image Result
    Graph showing lipid peroxidation levels in each subgroup.

    Graph showing lipid peroxidation levels in each subgroup.

PII: S0090-3019(05)00387-3

doi: 10.1016/j.surneu.2005.04.047

Surgical Neurology
Volume 65, Issue 1 , Pages 42-47 , January 2006

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